Acute Kidney Injury in COVID-19 Patients Insights from Colombian Study Using GENIUS 90 Technology

Introduction:
Acute kidney injury (AKI) is a critical complication in severe COVID-19 cases, affecting up to 40% of patients. A recent study conducted in Colombia analyzed the clinical and laboratory characteristics of COVID-19 patients who developed AKI and received renal replacement therapy using the GENIUS® 90 technology.

Key Findings:

  • Patient Demographics: 78.9% were male, with an average age of 64 years.
  • Common Comorbidities: Hypertension (65.3%), diabetes mellitus (38.9%), and obesity (26.3%).
  • Inflammatory Markers: Elevated levels of CRP (20.3 mg/dl), d-dimer (931 mcg/L), and ferritin (1174 ng/ml).
  • Renal Replacement Therapy: 63.5% received sustained low-efficiency dialysis (SLED), while 36.5% underwent conventional hemodialysis.
  • Mortality Rate: 36.9% overall, with a lower mortality in CKD patients (18.7%) compared to non-CKD patients (40.1%).

Significance of GENIUS® 90 Technology
The study highlights the potential benefits of intermittent and prolonged renal replacement therapy in managing AKI in critically ill COVID-19 patients. GENIUS® 90 offers a safe, effective, and cost-efficient alternative to traditional continuous therapies.

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