Introduction:
Renal tuberculosis (TB) remains an elusive entity, often masquerading as other conditions, leading to diagnostic delays. This case study presents a 15-year-old male with a complex clinical presentation that ultimately led to the diagnosis of renal TB. The case highlights the importance of integrating clinical, radiological, microbiological, and histopathological findings to ensure early detection and treatment.
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Case Summary:
- Patient Profile: 15-year-old male from Agra, India
- Symptoms:
- Intermittent low-grade fever (15 days)
- Unexplained weight loss (10 kg in 5 months)
- Fatigue and skin rashes (2 months)
- No respiratory or urinary symptoms
- Diagnostic Journey:
- Initial misdiagnosis as enteric fever
- Persistent symptoms led to advanced testing
- Elevated ESR, CRP, and urea/creatinine levels
- Renal biopsy revealed non-necrotizing granulomatous interstitial nephritis
- Acid-fast bacillus polymerase chain reaction (AFB-PCR) positive for Mycobacterium tuberculosis
- Treatment Plan:
- Standard TB regimen: Rifampicin, Isoniazid, Pyrazinamide, and Ethambutol (6 months)
- Close follow-up and adherence counseling
Key Takeaways on Renal TB
Atypical Presentation: Genitourinary TB often lacks classical urinary symptoms.
Early Diagnosis is Crucial: Delayed detection can lead to renal failure.
Comprehensive Testing: Biopsy and AFB-PCR significantly aid in confirming renal TB.
Treatment Adherence Matters: Standard anti-TB therapy ensures positive outcomes.
External Medical Reference:
The World Health Organization (WHO) emphasizes the importance of early diagnosis and standardized treatment for genitourinary tuberculosis to prevent long-term complications.
Further Reading & References:
Read the full study: https://doi.org/10.29328/journal.jcn.1001126
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Call to Action:
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Disclaimer: This content is generated using AI assistance and should be reviewed for accuracy and compliance before considering this article and its contents as a reference. Any mishaps or grievances raised due to the reusing of this material will not be handled by the author of this article.


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