Autologous Hematopoietic Stem Cell Transplantation: Insights from King Fahad Specialist Hospital’s Experience

Introduction: Autologous hematopoietic stem cell transplantation (HSCT) remains a cornerstone in treating multiple myeloma, offering improved survival outcomes. A recent study from King Fahad Specialist Hospital in Dammam, Saudi Arabia, explores the efficacy and safety of HSCT using both cryopreserved and non-cryopreserved stem cells. Visit https://www.stemcelltherjournal.org/jsctt for more groundbreaking research in this field.

Key Findings from the Study

• Study Scope & Methods: A retrospective study was conducted on 119 multiple myeloma patients who underwent 135 autologous HSCTs over an 11-year period.
• Survival Rates: 100-day post-transplant survival was 100%, while 4-year overall survival (OS) and progression-free survival (PFS) were 82% and 68%, respectively, for non-cryopreserved transplants.
• Non-Cryopreserved HSCT: The study confirms that HSCT without cryopreservation is safe and effective, reducing costs and enabling outpatient procedures.
• High-Risk Factors: 31.93% of patients had adverse cytogenetics, while 60.50% presented with advanced bone disease.

Medical Perspectives on Stem Cell Transplantation The American Society of Hematology (ASH) highlights the role of autologous HSCT as a preferred treatment for multiple myeloma patients. Similarly, the International Society for Stem Cell Research (ISSCR) stresses the importance of improving HSCT methodologies to enhance patient outcomes.

For a detailed analysis of the findings, read the full study at https://doi.org/10.29328/journal.jsctt.1001027.

Additionally, explore related topics on our website:

• Advancements in Stem Cell Therapy
• The Role of Outpatient HSCT in Modern Medicine
• Challenges and Future Prospects of HSCT

A comprehensive review is available in our main journal article at https://www.stemcelltherjournal.org/jsctt.

Future Implications and Call-to-Action The findings suggest that non-cryopreserved autologous HSCT could become a cost-effective alternative without compromising efficacy. As research progresses, further refinements in transplantation methods may improve patient outcomes globally.

Explore more studies at https://www.stemcelltherjournal.org/jsctt and join the discussion in the comments below!

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