Understanding Dose Distribution and Second Cancer Risk in Radiotherapy with 60Co Teletherapy Beam

Key Findings of the Study

  • The study used a male Alderson Rando Phantom and thermoluminescence dosimeters (TLDs) to measure in-field and out-of-field radiation doses.
  • Target organs (lungs and stomach) received precise radiation doses of 100 cGy and 200 cGy using a 60Co teletherapy unit.
  • The depth dose correction factor for lung cancer treatment was determined as 0.8667 ± 0.01, while for the stomach, it was 0.7856 ± 0.017.
  • Peripheral organs, such as the liver and colon, received significant outfield doses, increasing the risk of secondary malignancies.

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Risk Estimation for Second Cancer Using the Linear No-Threshold (LNT) model, the study estimated second cancer risks:

  • Lung irradiation: Stomach received the highest peripheral dose (96.60 mSv), with a risk factor of 139.1 × 10^-3.
  • Stomach irradiation: The liver absorbed the highest dose (96.35 mSv), with a risk factor of 138.7 × 10^-3.
  • Shielding techniques are recommended to protect adjacent organs like the kidney and pancreas during radiotherapy.

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