Rare Case of Primary Follicular Lymphoma in the Ascending Colon: A Surgical Perspective

Introduction: Primary follicular lymphoma of the gastrointestinal tract is an uncommon yet significant malignancy requiring prompt diagnosis and intervention. In this blog, we explore a rare case of primary follicular lymphoma arising from the ascending colon, its clinical presentation, and the crucial role of surgery in treatment. Visit https://www.clinmedcasereportsjournal.org/acr for more groundbreaking research in this field.

Case Summary: A 63-year-old male presented with abdominal pain, bloating, vomiting, chronic constipation, and a significant weight loss of 20 kg over two months. A physical examination revealed a firm mass in the right lower quadrant. Diagnostic imaging confirmed a 100x56x95 mm mass in the ascending colon, leading to a right hemicolectomy followed by chemotherapy.

Clinical Findings and Diagnosis:

• A large vegetative lesion detected via colonoscopy
• Histopathological and immunohistochemical findings confirmed follicular lymphoma (CD20, BCL2, and CD10 positive)
• No evidence of metastasis

Treatment and Outcome: The patient underwent surgical resection with a right hemicolectomy and subsequent chemotherapy. Postoperative recovery was uneventful, and the patient was discharged after six days.

Understanding Primary Colonic Lymphoma:

• Accounts for <1% of all colorectal malignancies
• More common in males, typically diagnosed in the 6th and 7th decades of life
• The cecum is the most affected region due to abundant lymphatic tissue

Strategic Medical Insights: The American Cancer Society (ACS) emphasizes the importance of early detection and appropriate multidisciplinary management for gastrointestinal lymphomas. Colonoscopy remains a key diagnostic tool, but surgical intervention is often necessary for conclusive diagnosis and treatment.

Read More: Explore the full case study at https://doi.org/10.29328/journal.acr.1001065. For more related studies, visit our case reports section.

Call-to-Action (CTA): Stay informed about rare medical cases and innovative treatments. Visit https://www.clinmedcasereportsjournal.org/acr for more insights and join the conversation by sharing your thoughts in the comments below!

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