Exploring the Link: Carotidynia and Cancer Treatment

Case Study Summary A 64-year-old woman with ovarian cancer developed symptoms of carotidynia—including fever, elevated inflammatory markers, and neck pain—nine days post-chemotherapy and G-CSF administration. Imaging confirmed soft tissue swelling around the carotid artery. Treatment with glucocorticoids and antibiotics led to symptom resolution within a week.

Potential Link Between Carotidynia and Cancer Therapy

  • Delayed Onset: Symptoms appeared days after chemotherapy and G-CSF administration.
  • Inflammatory Response: Elevated CRP levels and white blood cell count suggest a severe inflammatory reaction.
  • Similar Cases: While paclitaxel has not previously been linked to carotidynia, other taxanes (e.g., docetaxel) and G-CSF have been implicated.

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