Introduction The fungal pathogen Sclerotinia sclerotiorum is a notorious culprit behind stem rot disease in Brassica crops, causing significant yield losses. A recent study utilized UPLC-Q-TOF-MS to conduct untargeted metabolite profiling of this pathogen under axenic conditions, shedding light on its virulence mechanisms.
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Key Findings: Metabolite Profiling of S. sclerotiorum
- The study identified ten major secondary metabolites, including sclerin, sclerotinin-B, sclerone, melanin, and botcinic acid.
- Six metabolites—gliovirin, scleramide, botcinic acid, bostrycoidin, botcinin A, and botcinin D—were reported for the first time in S. sclerotiorum culture.
- A comparative analysis revealed that metabolite secretion varied among pathogen isolates and was independent of their virulence levels.
Implications for Plant Pathology Understanding the metabolic diversity of S. sclerotiorum could pave the way for novel disease management strategies. The American Phytopathological Society (APS) highlights the importance of such research in developing resistant crop varieties and targeted fungicides.
Access the Full Study Read the full study at https://doi.org/10.29328/journal.jpsp.1001095.
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