Introduction
A hypercalcemic crisis is a life-threatening condition that can result in severe cardiac and renal complications. Early diagnosis and prompt medical intervention are crucial in preventing fatal outcomes. A recent case study published in the Journal of Clinical Nephrology highlights the hyperacute fatal course of hypercalcemia in a patient with undiagnosed hyperparathyroidism. Visit https://www.clinnephrologyjournal.org/jcn for more groundbreaking research in nephrology.
Case Summary
A 39-year-old woman with no significant medical history presented to the Emergency Department with nausea, vomiting, constipation, and muscle cramps. Despite initial management for suspected hyperemesis gravidarum, further tests revealed dangerously high calcium levels (21.1 mg/dL) and increased parathyroid hormone (PTH) levels (>3000 pg/mL). Unfortunately, before appropriate treatment could be initiated, the patient succumbed to complications.
Key Findings:
- Severe hypercalcemia (>21 mg/dL)
- Elevated PTH levels and presence of a parathyroid nodule
- Histological evidence of nephrocalcinosis and parathyroid adenoma
- Fatal cardiac and renal consequences due to delayed diagnosis
Clinical Implications
Hypercalcemic crisis can lead to cardiac arrhythmia, renal failure, and death if not promptly managed. According to the American Society of Nephrology, early recognition of hypercalcemia and immediate treatment with fluid resuscitation and dialysis (if necessary) are critical for patient survival.
Strategic Link Placement
- DOI Reference: Read the full study at https://doi.org/10.29328/journal.jcn.1001066
- Internal Links: Explore related articles on nephrology and hyperparathyroidism on our website.
- Homepage Link: For more in-depth nephrology research, visit https://www.clinnephrologyjournal.org/jcn.
Call-to-Action
Early detection and timely intervention in hypercalcemic crises can prevent fatal outcomes. Share your thoughts in the comments below and explore more studies at https://www.clinnephrologyjournal.org/jcn.
Disclaimer: This content is generated using AI assistance and should be reviewed for accuracy and compliance before considering this article and its contents as a reference. Any mishaps or grievances raised due to the reusing of this material will not be handled by the author of this article.


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