The Impact of Interdialytic Weight Gain on Cardiovascular Health in Hemodialysis Patients

Introduction: Patients undergoing hemodialysis often experience significant volume shifts that can impact cardiovascular health. A recent study explores how interdialytic weight gain (IDWG) correlates with left ventricular hypertrophy (LVH) and fibroblast growth factor 23 (FGF-23) in end-stage renal disease (ESRD) patients. Understanding these relationships is crucial for improving patient outcomes. Visit https://www.clinnephrologyjournal.org/jcn for more insights into nephrology research.

Key Findings:

• Higher IDWG Linked to Cardiovascular Risks: Patients with a weight gain of ≥ 3 kg had higher systolic blood pressure and LVH compared to those with lower IDWG.
• FGF-23 as a Marker for Volume Overload and LVH: The study found a positive correlation between FGF-23 levels and IDWG, systolic and diastolic blood pressure, left ventricular mass index (LVMI), and posterior wall thickness.
• Association with Anemia: FGF-23 was negatively correlated with hemoglobin levels, suggesting a potential role in anemia among ESRD patients.

Medical Implications: The National Kidney Foundation emphasizes that proper fluid management in hemodialysis is crucial to reducing cardiovascular complications and improving patient survival. Strategies such as dietary sodium restriction and personalized ultrafiltration rates can help manage fluid balance effectively.

Read the Full Study: For a comprehensive analysis, access the full research article at https://doi.org/10.29328/journal.jcn.1001057.

Further Reading:

• Understanding the Role of FGF-23 in Chronic Kidney Disease: Related Article
• Managing Fluid Overload in Hemodialysis Patients: Expert Insights

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