Serum Creatinine Fluctuations in CKD Patients Preoperative and Postoperative Insights

Introduction:
Serum creatinine plays a crucial role in assessing kidney function, particularly in chronic kidney disease (CKD) patients undergoing surgery. A recent study explores the factors influencing creatinine fluctuations before and after surgery, providing valuable insights for clinicians and patients alike. Visit https://www.clinnephrologyjournal.com/jcn for more groundbreaking research in nephrology.

Preoperative and Postoperative Serum Creatinine Variations
Chronic Kidney Disease (CKD) affects millions worldwide, necessitating careful monitoring of renal function during surgical interventions. This study evaluates how serum creatinine levels change due to factors such as:

• Preoperative immobilization
• Comorbidities (e.g., diabetes, hypertension, dyslipidemia)
• Prolonged hospital stays
• Medication use, including NSAIDs and antibiotics

Key Findings:

• Among the 37 patients studied, 22 had normal renal function at admission, but 10 experienced creatinine elevations after prolonged hospitalization.
• CKD-diagnosed patients showed minor postoperative creatinine fluctuations, while normal patients exhibited greater variations.
• Factors like immobilization, dehydration, and medication use played significant roles in creatinine changes.

External Reference:
The National Kidney Foundation (NKF) emphasizes that maintaining stable kidney function requires careful monitoring of medications and hydration levels during hospitalization.

DOI and Further Reading:
For a detailed analysis, read the full study at https://doi.org/10.29328/journal.jcn.1001102.

Clinical Implications:

• Patients with CKD need preoperative dialysis considerations.
• Postoperative monitoring should focus on preventing sudden creatinine elevation through proper hydration and medication management.
• Surgeons and anesthesiologists should collaborate with nephrologists to ensure optimal patient outcomes.

Conclusion & Call to Action:
Serum creatinine fluctuations can impact surgical outcomes in CKD patients. Clinicians must be aware of contributing factors to manage risks effectively. Explore more studies at https://www.clinnephrologyjournal.com/jcn and share your thoughts in the comments below!

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