Treatment for Hepatitis C in Hemodialysis Patients A Study from Morocco

Key Findings from the Study:

  • The study included 20 hemodialysis patients with chronic HCV infection, treated with a combination of SOF (400 mg, thrice weekly) and Daclatasvir (DAC, 60 mg daily) for 12 to 24 weeks.
  • 100% of patients achieved a sustained virological response (SVR), indicating the treatment’s effectiveness.
  • The regimen was well-tolerated, with only mild side effects such as fatigue and headaches, which resolved post-treatment.
  • No patients discontinued treatment due to adverse effects or experienced hepatobiliary or cardiac toxicity.
  • The study highlights that despite the absence of newer, renally safe direct-acting antivirals (DAAs) in Morocco, SOF-based treatment remains a viable option.

Clinical Implications and External Perspectives: The American Association for the Study of Liver Diseases (AASLD) emphasizes the importance of personalized HCV treatment strategies for patients with renal impairment. Incorporating DAAs tailored for hemodialysis patients can significantly improve treatment outcomes while minimizing side effects.

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