Mechanisms & Clinical Insights

Understanding Intermittent Left Bundle Branch Block
A 73-year-old male underwent cardiologic evaluation due to an incidental electrocardiographic finding of LBBB. Despite being asymptomatic and having no relevant cardiac history, a 12-lead Holter ECG revealed intermittent LBBB, triggered by a premature ventricular complex (PVC). This discovery prompted a deeper examination of the underlying electrophysiological mechanism.

Mechanism Behind the Intermittent LBBB

  • The study identified the linking phenomenon as a key mechanism, where repetitive concealed retrograde penetration of the left bundle leads to functional block.
  • The disappearance of LBBB after a PVC suggests a resetting effect, allowing the left bundle branch to recover its conduction properties.
  • Factors influencing this occurrence include:
    • Post-extrasystolic pause allowing the blocked bundle to recover from refractoriness.
    • Disruption of retrograde concealed conduction through the right bundle.

Key Takeaways:

  • Intermittent LBBB can result from functional rather than structural abnormalities.
  • The linking phenomenon plays a significant role in its manifestation.
  • PVCs may interrupt aberrant conduction, revealing the presence of functional LBBB.
  • A detailed clinical assessment is essential to rule out underlying cardiac conditions.

Further Reading & Resources:

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