Subacute Infectious Endocarditis and Membranoproliferative Glomerulonephritis A Rare Case Study

Introduction: Subacute infectious endocarditis (SIE) is a severe condition that can lead to secondary complications such as membranoproliferative glomerulonephritis (MPGN). This case report highlights the diagnosis, treatment, and recovery of a 57-year-old male patient diagnosed with SIE-induced MPGN. Understanding such cases is crucial for early diagnosis and improved patient outcomes. Visit https://www.cardiologymedjournal.com/jccm for more cutting-edge research in cardiology and cardiovascular medicine.

Clinical Case and Findings: A 57-year-old male farmer experienced fatigue, appetite loss, and hematuria for over a month. Despite no history of cardiac issues, echocardiography revealed mitral valve prolapse with perforation, vegetation, and severe regurgitation. A renal biopsy confirmed MPGN, and laboratory results indicated mild proteinuria, elevated serum creatinine, and anemia.

Key Takeaways:

• Symptoms: Fatigue, gross hematuria, mild edema, intermittent fever
• Lab Findings: Mild proteinuria (1.04 g/day), RBC dysmorphia (543/HP), serum creatinine (1.46 mg/dL)
• Diagnosis: SIE-associated MPGN confirmed through echocardiogram and renal biopsy
• Treatment: Intravenous antibiotics followed by mitral valve replacement surgery

External Medical Insights: According to the American Heart Association (AHA), timely diagnosis and antibiotic therapy play a vital role in managing infective endocarditis. Delayed treatment can lead to severe complications, including irreversible renal damage.

Strategic Link Placement: For a detailed analysis, read the full study at https://doi.com/10.29328/journal.jccm.1001014.

Treatment Approach and Outcomes:

• Initial Therapy: Cefoperazone sodium and teicoplanin were administered immediately upon diagnosis.
• Surgical Intervention: Mitral valve replacement surgery was performed.
• Follow-up Results: One year post-operation, the patient exhibited full renal function recovery with normal serum creatinine levels.

Conclusion: This case highlights the importance of early detection and aggressive treatment of SIE-induced MPGN. Physicians should consider thorough cardiac evaluations in patients presenting with renal symptoms. Explore more case studies and research at https://www.cardiologymedjournal.com/jccm and share your thoughts in the comments below!

Disclaimer: This content is generated using AI assistance and should be reviewed for accuracy and compliance before considering this article and its contents as a reference. Any mishaps or grievances raised due to the reusing of this material will not be handled by the author of this article