Symptom-Driven Coronary Angiography After Drug-Eluting Balloon Treatment

Introduction: Managing in-stent restenosis (ISR) remains a critical challenge in interventional cardiology. Drug-eluting balloons (DEB) have emerged as a promising treatment option for ISR in patients with drug-eluting stents (DES). A recent study investigates the incidence of symptom-driven coronary angiography (SDCA) post-DEB treatment and its implications.

Key Findings from the Study:

  • The study evaluated 28 patients who underwent DEB treatment for DES-ISR.
  • SDCA occurred in 54% of patients within two years of follow-up.
  • Within the first year, 11% required SDCA with target lesion revascularization (TLR), while 36% had SDCA without TLR.
  • 30% of patients undergoing SDCA without TLR had acute coronary syndrome (ACS) but did not require percutaneous coronary intervention (PCI).

Clinical Implications and Considerations:

  • High Cardiovascular Risk Group: The findings highlight that patients requiring SDCA may represent a subgroup with higher cardiovascular risk.
  • Importance of Non-Invasive Imaging: Alternative imaging modalities could help reduce unnecessary angiographic procedures.
  • Need for Larger Studies: The study suggests that more extensive research is necessary to validate SDCA as a meaningful clinical marker.

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