TIMI vs GRACE Score Which Predicts Mortality in NSTEMI Patients More Accurately

Understanding TIMI and GRACE Scores
Both the Thrombolysis in Myocardial Infarction (TIMI) risk score and the Global Registry of Acute Coronary Events (GRACE) risk score are used for early risk stratification in NSTEMI patients. The TIMI score assesses patient history and clinical presentation, while the GRACE score incorporates additional parameters, including laboratory findings and hemodynamic status.

Study Findings: Comparing Diagnostic Accuracy
A study conducted at the CPE Institute of Cardiology assessed 372 NSTEMI patients to determine which scoring system better predicts mortality. Key findings include:

  • The mean age of patients was 55.73±9.78 years, with a male-to-female ratio of 1.6:1.
  • Diabetes (39%), smoking (14.2%), and hypertension (46.8%) were the most common risk factors.
  • TIMI Score Results:
    • Sensitivity: 97.7%
    • Specificity: 92.93%
    • Diagnostic Accuracy: 95.16%
  • GRACE Score Results:
    • Sensitivity: 100%
    • Specificity: 95.96%
    • Diagnostic Accuracy: 97.85%

Clinical Implications
The study concluded that both scoring systems are highly effective in predicting mortality, but GRACE demonstrated superior diagnostic accuracy. This supports existing literature that GRACE provides a more comprehensive assessment of risk.

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