How Regular Blood Donation Impacts Lipid and Hematological Profiles

Key Findings from the Study The study examined 120 male participants aged 18-60, categorized into three groups:

  • Regular donors (those who donated 3-4 times a year for at least two consecutive years)
  • First-time donors
  • Non-donors

Lipid Profile Results:

  • Regular blood donors had significantly lower total cholesterol (169 mg/dl) compared to first-time donors (198 mg/dl) and non-donors (202 mg/dl).
  • Triglyceride levels were lowest in regular donors (116 mg/dl), while first-time donors and non-donors showed elevated levels (179 mg/dl and 180 mg/dl, respectively).
  • LDL (low-density lipoprotein) levels were significantly lower in regular donors (92 mg/dl) compared to first-time donors (120 mg/dl) and non-donors (125 mg/dl).
  • HDL (high-density lipoprotein), known as ‘good cholesterol,’ was highest in regular donors (54 mg/dl) compared to non-donors (41.75 mg/dl).
  • LDL/HDL and TC/HDL ratios were significantly lower in regular donors, reducing their risk of cardiovascular disease.

Hematological Profile Insights:

  • Erythrocyte Sedimentation Rate (ESR), a marker for inflammation, was significantly lower in regular donors (6.63 mm/hr) compared to first-time donors (7.4 mm/hr) and non-donors (7.6 mm/hr).
  • Hematocrit (HCT) levels were also significantly lower in regular donors (42.98%) than in first-time donors (44.63%) and non-donors (44.75%).

These findings suggest that regular blood donation can lower cholesterol levels and inflammation markers, potentially reducing the risk of heart disease.

The Role of Blood Donation in Preventive Healthcare Blood donation programs not only support medical needs but may also benefit donors by reducing excess iron levels, lowering cholesterol, and improving cardiovascular health. Encouraging regular donation could be an effective public health strategy.

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