P Wave Dispersion in Patients with Premenstrual Dysphoric Disorder

Introduction

Premenstrual Dysphoric Disorder (PMDD) is a severe form of premenstrual syndrome (PMS) characterized by significant mood disturbances, including anxiety, irritability, and depression. Recent research has highlighted a potential link between PMDD and cardiac abnormalities, particularly concerning P wave dispersion (Pd)—an electrocardiographic marker for atrial fibrillation risk.

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Key Findings from the Study

A recent study examined P wave dispersion in 25 female patients with PMDD and a control group of 25 healthy women. The primary results revealed:

• Higher Pmax and Pmin values in patients with PMDD compared to healthy subjects.
• Significantly increased Pd levels in PMDD patients, indicating a possible predisposition to cardiac arrhythmias.
• No substantial correlation between Pd and sociodemographic variables.

These findings suggest that women with PMDD may have an increased risk of cardiac irregularities, emphasizing the importance of cardiovascular monitoring in this population.

The Link Between Anxiety and Cardiac Health

Studies have shown that anxiety-related disorders often influence cardiac function. The American Heart Association (AHA) recognizes the impact of psychological stress on cardiovascular health, noting that stress can trigger physiological responses leading to arrhythmias and other heart conditions.

Implications for Clinical Practice

This study underscores the need for:

• Routine ECG monitoring in patients diagnosed with PMDD.
• A multidisciplinary approach integrating psychiatric and cardiology evaluations.
• Further longitudinal studies with larger samples to validate findings.

Read the Full Study

Access the complete research article at: https://doi.com/10.29328/journal.jccm.1001046.

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