Preclinical Stiff Heart A Silent Predictor of Cardiovascular Risk

Key Findings of the Study A study conducted at Rouen University Hospital analyzed 353 patients with no significant heart disease. Key insights include:

  • Higher Risk of Cardiac Events: Patients with predominant stiff heart had a 2.9x higher risk of heart failure and a 5.8x higher risk of cardiac death compared to those with mild relaxation abnormalities.
  • Prevalence of Diastolic Dysfunction: 95% of the study participants exhibited diastolic dysfunction, with 39% classified as having a predominant stiff heart.
  • Prognostic Importance: Stiff heart was a stronger predictor of cardiovascular outcomes than isolated relaxation abnormalities.

Future Implications and Research Identifying patients with preclinical stiff heart allows for early interventions, such as lifestyle modifications and targeted medical therapies. Advanced diagnostic tools, including cardiac shear wave elastography, are paving the way for non-invasive detection.

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