Aortic Dissection Leading to Two Myocardial Infarctions A Rare but Fatal Case

Case Summary: A 56-year-old obese male with a history of hypertension was admitted with sudden right-sided chest pain radiating to his right shoulder and arm. Initial electrocardiography (ECG) findings suggested an inferior ST-segment elevation myocardial infarction (STEMI). He was treated with standard thrombolytic therapy, resulting in symptom relief. However, within 30 minutes, he developed left-sided chest pain and ECG changes indicating an anterior STEMI. Coronary angiography later revealed a long dissection in the left circumflex artery (RCX) and an occluded left anterior descending artery (LAD), ultimately leading to a Stanford Type A aortic dissection. Despite emergency transfer for surgical intervention, the patient succumbed to refractory cardiogenic shock.

Understanding the Clinical Significance:

  • Early Diagnosis is Critical: Diagnosing aortic dissection is challenging as symptoms often mimic myocardial infarction. Physicians must consider aortic dissection in cases presenting with atypical chest pain and fluctuating ECG changes.
  • Management Complexity: Coronary malperfusion complicates type A aortic dissection and increases mortality risk. Surgical intervention combined with aggressive coronary revascularization remains the best approach.

Key Takeaways:

  • Aortic dissection should be a differential diagnosis in patients with fluctuating ST-segment elevations.
  • Immediate imaging and a multidisciplinary approach are essential for effective management.
  • Antiplatelet and thrombolytic therapy should be used cautiously when aortic dissection is suspected.

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