Controlling Blood Pressure A Key Strategy to Prevent Atrial Fibrillation in Metabolic Syndrome Patients

Introduction

Blood Pressure and AF Risk

This observational study involved 435 patients aged between 45–79 years who were diagnosed with MS. They were categorized into two groups based on how well their blood pressure (BP) was controlled:

  • Group 1: Patients with controlled BP
  • Group 2: Patients with uncontrolled BP

Key Findings:

  • New-onset AF occurred in 34.7% of patients with uncontrolled BP compared to 19.5% with controlled BP.
  • Persistent and permanent forms of AF were significantly more common among those with uncontrolled BP.
  • Uncontrolled BP was associated with:
    • 2.2 times higher odds of AF
    • 3.9 times higher odds of persistent AF
    • 4.1 times higher odds of permanent AF
    • Increased left atrial size and body mass index (BMI)

Implications for Clinical Practice

Takeaways

  • Metabolic Syndrome and AF are closely linked.
  • Controlling BP can cut AF risk by over 30%.
  • Persistent and permanent AF forms are largely preventable with effective BP management.
  • Increased BMI and LA enlargement are key predictors.

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