Does Global Longitudinal Strain Improve Stratification Risk in Heart Failure with Preserved Ejection Fraction

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  • Key Findings:
    • The study investigated 153 patients, revealing that 63% had impaired GLS (<16%).
    • Despite hypotheses, GLS did not predict cardiovascular events in the HFPEF cohort.
    • Key prognostic factors identified were congestive venous signs, anemia, and pulmonary hypertension.
  • Implications:
    • Global longitudinal strain, while useful in other forms of heart failure, did not show strong prognostic value for HFPEF in this study.
    • Factors like anemia and pulmonary hypertension are more reliable indicators in this context.
  • Statistical Insights:
    • GLS was measured at rest and did not correlate with functional capacity or adverse outcomes.
    • The study highlights the need for further research with larger sample sizes and exercise-induced GLS evaluations.

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