A Rare Case of Beta Thalassemia with Right Ventricular Outflow Tract Tachycardia Insights into Cardiac Complications

Introduction: In a groundbreaking study, a 20-year-old female with beta thalassemia major developed right ventricular outflow tract tachycardia (RVOT VT) as a result of iron overload, despite undergoing regular blood transfusions and chelation therapy. This case highlights the serious cardiac complications that can arise in thalassemia patients due to iron accumulation. For more in-depth research on related topics, visit https://www.cardiologymedjournal.com/jccm and explore further insights.

• Case Overview:
  • A 20-year-old female diagnosed with beta thalassemia major experienced recurrent breathlessness and palpitations. Despite regular blood transfusions and chelation therapy, she developed RVOT VT, a rare and life-threatening arrhythmia.
• Medical Management:
  • The patient was initially treated with amiodarone and underwent electrical cardioversion when chemical treatment failed. However, the arrhythmia persisted until an Automatic Implantable Cardioverter Defibrillator (AICD) was implanted, effectively preventing further episodes of VT over a four-year follow-up period.
• Iron Overload in Beta Thalassemia:
  • Beta thalassemia leads to chronic anemia, requiring frequent blood transfusions that can cause iron overload. This excess iron can accumulate in vital organs, including the heart, leading to complications such as cardiomyopathy and arrhythmias. In this case, iron deposits in the myocardium were a contributing factor to the patient’s VT.
• Cardiac Complications:
  • Iron overload affects the heart’s conduction system, disrupting normal electrical impulses. This case underscores the importance of early diagnosis and intervention in preventing severe cardiac outcomes in thalassemia patients.

Integration of External Medical Sources:

• The American College of Cardiology highlights the critical role of monitoring and managing iron overload in patients with beta thalassemia to prevent life-threatening cardiac complications. https://www.cardiologymedjournal jccm1001201

Further Reading and Resources

• For further information on the study, you can access the full article here
• Additionally, related research articles can be found on our https://www.cardiologymedjournal.com/jccm.

Call-to-Action Explore more studies at https://www.cardiologymedjournal.com/jccm and join the conversation by sharing your thoughts in the comments below!

Disclaimer: This content is generated using AI assistance and should be reviewed for accuracy and compliance before considering this article and its contents as a reference. Any mishaps or grievances raised due to the reusing of this material will not be handled by the author of this article.