Unveiling the Challenges Managing Severe COVID 19 in Pregnant Women Insights from a UAE Case Series

Introduction

COVID-19 reshaped global healthcare, but its impact on pregnant women presented unique clinical challenges. A recent study from Latifa Hospital, Dubai, offers critical insights into how severe and critical COVID-19 infections manifest and are managed during pregnancy.
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Key Findings from the Study

• Location: Latifa Women and Children Hospital, UAE
• Duration: Jan–June 2020
• Subjects: Seven pregnant women with severe/critical COVID-19
• Objective: Examine clinical features, treatment, and outcomes.

Common Clinical Presentations

• Fever (6/7 patients)
• Cough and breathing difficulties
• High inflammatory markers and signs of cytokine storm
• ARDS in 5 of 7 patients, requiring ventilation

Treatment Approaches

• Medications Used:
  • Antivirals, steroids, anticoagulants
  • Pegylated interferon (5/7), Tocilizumab (1/7)
  • ECMO used in one critical case
• Delivery:
  • All 5 third-trimester patients were delivered via emergency cesarean section due to maternal hypoxia
  • Neonatal outcomes were uniformly positive, with no COVID transmission detected

Outcomes

• Maternal:
  • 1 maternal death due to multi organ failure
  • Early treatment with steroids and anticoagulants showed better recovery patterns
• Neonatal:
  • All six neonates (including a twin set) were healthy, with negative COVID tests
  • Prematurity related jaundice resolved without complications

Broader Implications

The findings reinforce the necessity of tailored COVID-19 treatment strategies for pregnant patients. According to the Centers for Disease Control and Prevention (CDC), pregnancy can increase the risk of severe illness from COVID-19. Thus, early intervention, fetal monitoring, and interdisciplinary care are vital.

Study Access

Read the full study at: https://doi.org/10.29328/journal.cjog.1001071
A detailed analysis can be found in our main journal article.

Takeaways

• Pregnancy increases COVID-19 vulnerability due to physiological and immunological changes.
• Early intervention using antivirals, steroids, and anticoagulants can improve maternal and neonatal outcomes.
• Emergency cesarean delivery may be necessary in the face of maternal respiratory deterioration.
• No vertical transmission observed supporting safe pregnancy care with rigorous infection control.

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