Heighten Science Publications Inc.

Unveiling Patterns in Fetal Malformations Insights from a Multi Center Observational Study

—

by

Vishnu
in

Introduction

Understanding congenital anomalies is vital to shaping maternal-fetal healthcare. A recent multi centric study conducted at Beni Suef University Hospital sheds light on the prevalence and types of fetal malformations observed among over 20,000 pregnant women.
Visit https://www.obstetricgynecoljournal.com for more groundbreaking research in the field of obstetrics and gynecology.

Main Findings and Key Highlights

  • Study Overview:
    Conducted from 2016 to 2019 across multiple fetal medicine units, this prospective observational study screened 20,225 pregnant women via anatomical ultrasound scans.
  • Prevalence:
    • 183 cases (0.9%) had fetal congenital anomalies.
    • The most frequent anomalies were found in the nervous system (34.4%), followed by renal/genital (24.5%), GIT/anterior abdominal wall (20.2%), and cardiac (6.5%).
  • Maternal and Environmental Risk Factors:
    • Consanguinity was present in 31.1% of cases most notably in thoracic (55.6%) and skeletal (45%) anomalies.
    • Lack of folic acid intake was significantly associated with spinal and cephalic anomalies.
    • Urban residence showed higher incidences of thoracic and abdominal anomalies, while rural areas had more cephalic and cardiac defects.
  • Gestational Age and Survival:
    • Median gestational age at diagnosis was 24 weeks.
    • Survival varied by anomaly type: Skeletal anomalies had the highest 1 week survival rate (77.8%), while thoracic anomalies had the lowest (12.5%).
  • Conclusion:
    The study reinforces the importance of early prenatal screening and routine anomaly scans, especially for high-risk pregnancies.

Public Health Implication

The World Health Organization (WHO) emphasizes the global burden of congenital anomalies, advocating for early detection and preventive strategies. According to WHO, congenital anomalies cause approximately 276,000 neonatal deaths every year.

Further Reading and Resources

Call to Action

Explore more studies at https://www.obstetricgynecoljournal.com and join the conversation by sharing your thoughts in the comments below

Disclaimer: This content is generated using AI assistance and should be reviewed for accuracy and compliance before considering this article and its contents as a reference. Any mishaps or grievances raised due to the reusing of this material will not be handled by the author of this article

Comments

Leave a comment