Cost Effective Management of Pelvic Masses How ROMA Outperforms Traditional Clinical Risk Assessment

Introduction

Evaluating Cost-Effective Approaches in Pelvic Mass Management

Key Findings:

  • ROMA alone reduced healthcare costs by 3.3% compared to ICRA alone.
  • Combination of ROMA + ICRA reduced costs by 3.9%, making it even more cost-effective.
  • ROMA reduced the number of repeat surgeries by 63%, a major advantage in minimizing patient risks and overall expenses.

The Power of ROMA in Clinical Decision Making

The ROMA score, which combines serum CA125, HE4 biomarkers, and menopausal status, demonstrates:

  • Higher sensitivity (94%) in detecting epithelial ovarian cancer.
  • A Negative Predictive Value (NPV) of 99%, ensuring more accurate differentiation between benign and malignant pelvic masses.
  • A significant reduction in unnecessary surgeries when used as the primary assessment tool.

Financial Implications and Healthcare Savings

Cost Comparison Highlights:

  • ROMA testing led to a 55% increase in laboratory costs but significantly reduced expensive surgical procedures.
  • Laparoscopy costs were reduced by 4%, while laparotomy costs saw a 3.1% reduction.
  • Incorporating ROMA could lead to a 4.2%–5.6% decrease in overall healthcare expenditures in cases involving all cancer diagnoses.

Breakdown of Average Cost Reductions:

  • Laparoscopy: Savings of up to $142,523
  • Laparotomy: Savings of up to $25,151
  • Overall surgery: Savings of up to $167,674

Referral to Specialists

Using ROMA effectively changed referral pathways:

  • 64% increase in initial surgeries performed by gynecologic oncologists.
  • 17%-18% decrease in initial surgeries performed by general gynecologists.
  • Significant reduction in repeat surgeries, preventing unnecessary procedures and enhancing patient care quality.

The Broader Impact on Cancer Care Costs

Conclusion

The study underscores that using ROMA, either alone or alongside ICRA, leads to better patient triage, fewer repeat surgeries, and overall cost savings in the management of women with pelvic masses. As healthcare systems grapple with rising costs, integrating sensitive, reliable diagnostic tools like ROMA offers a pathway to both clinical excellence and economic sustainability.

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