EXIT Protocol in Action Saving Lives with Timely Intervention in Cervical Teratoma Cases

Introduction

Fetal cervical teratomas are rare but life-threatening tumors that demand precise prenatal diagnosis and immediate multidisciplinary intervention. A compelling case from Brazil showcases how a modified EXIT (Ex Utero Intrapartum Treatment) protocol ensured neonatal survival despite challenges like breech presentation and airway obstruction.

Understanding Cervical Teratomas

  • Teratomas are congenital tumors originating from germ cells.
  • Cervical teratomas account for less than 5% of fetal teratomas.
  • These tumors can cause polyhydramnios, airway obstruction, and fetal death if untreated.

Key Insight: Early detection via ultrasound or MRI can dramatically improve outcomes.

The EXIT Protocol A Lifesaving Innovation

  • The EXIT procedure allows partial fetal delivery while maintaining placental circulation, providing time to secure the airway.
  • Traditionally applied to fetuses with airway obstruction, it has evolved into a critical tool in fetal surgery.

Case Summary EXIT Success in Breech Position

  • A 31-week fetus was diagnosed with a 6.3 cm cervical mass via Doppler ultrasound.
  • MRI confirmed mass effects displacing the airway.
  • A multidisciplinary team executed a modified EXIT procedure during cesarean delivery.

Key Steps Taken

  • Epidural and general anesthesia for maternal stability.
  • Complete fetal extraction due to breech position.
  • Neonatal intubation before umbilical cord clamping.

Postoperative Outcomes and Surgical Success

  • Tumor excision occurred 6 days post-birth with no complications.
  • Histology confirmed a Grade 3 immature teratoma.
  • Infant discharged after 45 days—currently healthy with no recurrence.

Broader Implications for Prenatal Care

  • MRI and ultrasound are vital tools for early detection of cervical masses.
  • EXIT protocol offers a safe strategy for managing anticipated airway obstruction.
  • Without timely action, mortality from cervical teratomas may exceed 80%.

Further Reading and Resources

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