Tag: #aHUS

  • Plasma Therapy in aHUS Patient with SARS-CoV-2 Infection

    Plasma Therapy in aHUS Patient with SARS-CoV-2 Infection

    Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare condition characterized by complement-mediated thrombotic microangiopathy. Patients with aHUS who contract SARS-CoV-2 face a heightened risk of disease recurrence due to complement system activation. However, the management of such cases remains an area of ongoing research. This article explores a recent case study where convalescent plasma…

  • Eculizumab Failure and the Off-Label Use of Ravulizumab

    Eculizumab Failure and the Off-Label Use of Ravulizumab

    Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare and severe disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. This case report highlights a catastrophic form of aHUS that was unresponsive to Eculizumab and required the off-label use of Ravulizumab, leading to successful hematologic recovery but progression to end-stage kidney disease. For more…

  • Plasma Therapy in aHUS Patient with SARS CoV Infection from Journal of Clinical Nephrology

    Plasma Therapy in aHUS Patient with SARS CoV Infection from Journal of Clinical Nephrology

    Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare but severe condition that affects the complement system, leading to thrombotic microangiopathy and potential organ damage. Given the complexities of managing aHUS during a SARS-CoV-2 infection, this case study explores the successful use of convalescent plasma therapy in a patient with aHUS and COVID-19. Visit HSPIOA…