Tag: #AntibioticDiscovery

Introduction The discovery of bacterial heterotrimeric amidotransferase GatCAB has opened new frontiers in understanding protein biosynthesis and antibiotic development. This essential enzyme plays a critical role in the translation fidelity of pathogenic bacteria, catalyzing reactions that ensure accurate amino acid incorporation into proteins. Since GatCAB is absent in mammalian cytoplasm, it presents a promising therapeutic…