Tag: #Eculizumab

  • Eculizumab Failure and the Off-Label Use of Ravulizumab

    Eculizumab Failure and the Off-Label Use of Ravulizumab

    Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare and severe disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. This case report highlights a catastrophic form of aHUS that was unresponsive to Eculizumab and required the off-label use of Ravulizumab, leading to successful hematologic recovery but progression to end-stage kidney disease. For more…