Tag: #KidneyDisease
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Understanding the Risks and Safety of Ultrasound-Guided Kidney Biopsies in Children
IntroductionPercutaneous kidney biopsy is an essential diagnostic tool for various kidney diseases, yet it carries potential complications. A recent study published in the Journal of Clinical Nephrology explores the risks associated with ultrasound-guided percutaneous native kidney biopsies in children. The study provides critical insights into the prevalence of complications, risk factors, and necessary interventions to…
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How Secondary Hyperparathyroidism Treatment Improves Hemoglobin Levels and Reduces ESA Dependency in Hemodialysis Patients
IntroductionSecondary hyperparathyroidism (SHPT) is a common but often overlooked factor contributing to anemia in hemodialysis (HD) patients. A recent study examined the impact of SHPT treatment on hemoglobin levels and the need for erythropoiesis-stimulating agents (ESAs). Understanding this connection can help improve anemia management in HD patients. Visit https://www.clinnephrologyjournal.org/jcn for more groundbreaking research in nephrology.…
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Chronic Kidney Disease in Women Insights from a Hospital-Based Screening Study in Varanasi
Introduction Chronic Kidney Disease (CKD) is a growing global health concern, significantly affecting women due to unique physiological and reproductive factors. A recent cross-sectional screening conducted at a tertiary care hospital in Varanasi sheds light on the prevalence, risk factors, and early detection strategies for CKD among women. Visit Clinical Nephrology Journal for more groundbreaking…
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A Rare Yet Significant Cause of Kidney Disease in Children
Introduction: Membranoproliferative glomerulonephritis (MPGN) is a serious condition leading to chronic kidney disease (CKD) and end-stage renal disease (ESRD), particularly in children. Characterized by immune complex deposition in the glomerulus, this condition presents significant challenges in treatment and prognosis. The latest research sheds light on the urgency of early diagnosis and targeted therapies. Visit Clinical…
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A Case of FSGS Diagnosis Through Kidney Biopsy
Introduction Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a prevalent genetic disorder, affecting approximately 6% of kidney failure cases. While proteinuria is uncommon in ADPKD, significant proteinuria warrants further investigation to exclude coexisting glomerular diseases. This case highlights the challenges and diagnostic approach to a patient with ADPKD and nephrotic-range proteinuria. Visit Journal of Clinical…
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Rare Case of Dense Deposition Disease with Combined C3 and C4d Deposits in a Patient with MYH9 Mutation
Introduction Dense Deposition Disease (DDD) is a rare form of glomerulonephritis caused by dysregulation of the complement system. This case presents a young Emirati male diagnosed with DDD, featuring both C3 and C4d deposits—a rare occurrence. Adding to the uniqueness of this case, the patient also exhibited an MYH9 gene mutation. Case Summary A 26-year-old…
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Eculizumab Failure and the Off-Label Use of Ravulizumab
Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare and severe disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. This case report highlights a catastrophic form of aHUS that was unresponsive to Eculizumab and required the off-label use of Ravulizumab, leading to successful hematologic recovery but progression to end-stage kidney disease. For more…
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Calciphylaxis in Hemodialysis: A Rare but Life-Threatening Condition
Introduction Calciphylaxis is a rare and life-threatening vascular disorder primarily affecting patients with end-stage kidney disease (ESKD) undergoing long-term dialysis. It is characterized by calcific and thrombotic occlusion of small blood vessels, leading to extremely painful necrotic skin lesions. Despite its severity, clear guidelines for treatment are still lacking. A recent case study published in…
