Tag: #Nephrology
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Tacrolimus Formulations in Renal Transplant Recipients Which One is More Effectiv
Introduction Tacrolimus is a crucial immunosuppressant used to prevent organ rejection in renal transplant recipients. However, maintaining therapeutic levels is challenging due to individual patient variations. A recent study compared three tacrolimus formulations—Immediate-Release (TAC-IR), Extended-Release Capsules (TAC-XL), and Extended-Release Tablets (TAC-XR)—to evaluate their effectiveness in keeping drug levels within the therapeutic range (TTR). Visit Horizon…
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Plasma Therapy in aHUS Patient with SARS CoV Infection from Journal of Clinical Nephrology
Introduction Atypical Hemolytic Uremic Syndrome (aHUS) is a rare but severe condition that affects the complement system, leading to thrombotic microangiopathy and potential organ damage. Given the complexities of managing aHUS during a SARS-CoV-2 infection, this case study explores the successful use of convalescent plasma therapy in a patient with aHUS and COVID-19. Visit HSPIOA…
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Dialysis Program on Renal Treatment Modalities Choice from the Journal of Clinical Nephrolog
Introduction In Portugal, approximately 2,500 patients with end-stage chronic kidney disease (CKD stage 5) begin renal replacement therapy (RRT) each year. The choice between kidney transplantation (TX), hemodialysis (HD), peritoneal dialysis (PD), or conservative treatment (CT) is complex, impacting quality of life and long-term health outcomes. A recent study published in the Journal of Clinical…
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Diffuse Alveolar Hemorrhage A Rare but Serious Complication of Systemic Lupus Erythematosus
Introduction Diffuse Alveolar Hemorrhage (DAH) is a severe yet uncommon manifestation of Systemic Lupus Erythematosus (SLE), presenting a significant challenge in patient management. While pulmonary involvement in SLE is well-documented, DAH remains a rare complication, occurring in only 1% to 5.4% of lupus cases. Early diagnosis and aggressive treatment are crucial for survival. This article…
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Acute Kidney Injury in COVID-19 Patients Insights from Colombian Study Using GENIUS 90 Technology
Introduction:Acute kidney injury (AKI) is a critical complication in severe COVID-19 cases, affecting up to 40% of patients. A recent study conducted in Colombia analyzed the clinical and laboratory characteristics of COVID-19 patients who developed AKI and received renal replacement therapy using the GENIUS® 90 technology. Visit https://www.clinnephrologyjournal.com/jcn for more groundbreaking research in nephrology. Key…
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Unusual Presentation of Oxalate Nephropathy Causing Acute Kidney Injury A Case Report
Introduction Oxalate nephropathy is a rare but serious condition characterized by kidney damage due to oxalate crystal deposition. This case report highlights an unusual presentation of acute kidney injury (AKI) due to hyperoxaluria, emphasizing its diagnostic and treatment challenges. For more groundbreaking research, visit Journal of Clinical Nephrology. Case Summary A 68-year-old male with a…
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COVID-19 and Rhabdomyolysis Unveiling a Rare but Serious Complication
Introduction: COVID-19 has been widely studied for its impact on the respiratory system, but emerging research suggests that the virus can also lead to severe muscle damage, a condition known as rhabdomyolysis. This rare yet serious complication can result in acute kidney injury (AKI) and other systemic effects, necessitating timely recognition and management. Visit Journal…
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Unlocking the Role of Biomarkers in Acute Kidney Injury AKI
Introduction:Acute Kidney Injury (AKI) is a serious condition linked to high morbidity and short-term mortality. Traditionally, serum creatinine has been the gold standard for diagnosing AKI, but advancements in medical research have led to the discovery of novel biomarkers that improve early detection and treatment. These biomarkers play a critical role in assessing kidney function,…
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Is Beta 2 Urinary Microglobulin a Biomarker of Topographical Discrimination Between High and Low Urinary Tract Infections
Introduction Urinary tract infections (UTIs) are a common health concern, often diagnosed based on clinical symptoms and laboratory findings. However, distinguishing between high (pyelonephritis) and low (cystitis) UTIs can be challenging, particularly in children and certain patient populations. A promising approach explored in recent research is the use of beta 2 urinary microglobulin as a…
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Cytomegalovirus Infection in Native Kidney Biopsy A Rare Clinical Insight
Introduction Cytomegalovirus (CMV) infections are commonly associated with renal transplant cases, but their occurrence in native kidneys remains rare. This article explores a case of CMV infection in a native kidney biopsy, shedding light on its clinical implications and diagnosis. For more groundbreaking research in nephrology, visit HSPIOA. Case Overview A 61-year-old woman with a…
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