Tag: #Thalassemia
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Impact of Alloimmunization on Transfusion-Dependent Patients: Risks, Challenges, and Emerging Solutions
Introduction Red blood cell (RBC) transfusions remain a life-saving therapy for patients with thalassemia major and sickle cell disease (SCD), but repeated transfusions often lead to alloimmunization, a serious complication where the immune system attacks donor blood. This can cause delays, transfusion reactions, and increased mortality risks. Understanding the mechanisms and prevention strategies is crucial…
