Tag: #TransplantMedicine
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Gene Expression in Renal Allograft Rejection How Urine Testing Could Transform Kidney Transplant Monitoring
Introduction Kidney transplantation remains one of the most effective treatments for patients with end-stage renal disease, but long-term graft survival is still threatened by immune-mediated rejection. A groundbreaking study explored how gene expression patterns in blood, kidney biopsy tissue, and urine can help identify acute and chronic renal allograft rejection more effectively and less invasively.…
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Post-Transplant Malignancy Risks, Prevention, and Management Strategies
Introduction: Post-transplant malignancy is one of the most concerning complications following Solid Organ Transplantation (SOT). The interplay between immunosuppressants, viral infections, and immune system modulation significantly contributes to cancer development in transplant recipients. As the demand for organ transplantation rises, understanding post-transplant malignancies, their risk factors, and prevention strategies becomes crucial. Visit Clinical Nephrology Journal…
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Pure Red Cell Aplasia – Post Major ABO Incompatible Allogenic Stem Cell Transplantation: Role of Ibrutinib
Introduction: Pure Red Cell Aplasia (PRCA) is a recognized complication following major ABO-incompatible allogeneic stem cell transplantation (HSCT). Characterized by anemia, reticulocytopenia, and the absence of erythroblasts in the bone marrow, PRCA can significantly impact patient outcomes. Recent research explores Ibrutinib as a novel therapeutic option for managing PRCA post-HSCT, showing promising results in restoring…
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